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The pharmaceutical applications of powder technology have long been recognized. Yet while many books focus on aspects of powder formation and behavior, there are few texts that explore the power of particulate science in the design, manufacture, and control of quality medicines. This revision discusses key principles and practical applications. The authors cover particulate material, its form and production, sampling from bodies of powder, particle size descriptors and statistics, behavior of particles and powder, instrumental analysis, particle size measurement and synergy of adopted techniques, and in vitro and in vivo performance criteria. Case studies are included in this new edition. This fully revised edition:
Provides an essential account of particulate science including several new chapters on multicomponent particles, regulatory considerations and product development
Presents a variety of topics ranging from the quality of published data on particle size in pharmaceuticals to the future of crystal engineering
Reviews methods of particle measurement and their importance for specific applications
Discusses misconceptions and misunderstandings of particulate science together with lessons from other industries
The pharmaceutical applications of powder technology have long been recognized. Yet while many books focus on aspects of powder formation and behavior, there are few texts that explore the power of particulate science in the design, manufacture, and control of quality medicines. This revision discusses key principles and practical applications. The authors cover particulate material, its form and production, sampling from bodies of powder, particle size descriptors and statistics, behavior of particles and powder, instrumental analysis, particle size measurement and synergy of adopted techniques, and in vitro and in vivo performance criteria. Case studies are included in this new edition. This fully revised edition:
Provides an essential account of particulate science including several new chapters on multicomponent particles, regulatory considerations and product development
Presents a variety of topics ranging from the quality of published data on particle size in pharmaceuticals to the future of crystal engineering
Reviews methods of particle measurement and their importance for specific applications
Discusses misconceptions and misunderstandings of particulate science together with lessons from other industries
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