In this edited volume, the authors present rich case studies of place-based philanthropy in the United States and Canada that make a strong conceptual and empirical argument for the importance, and growing imperative, of place-based philanthropy in 2023 and beyond. Offering a multidisciplinary theoretical grounding in the connection between philanthropy and place, the case studies range from foundations engaged in disaster recovery, a First Nations UNESCO site, to a funder collaborative engaging seven philanthropies targeting 30 neighborhoods in Montreal, and a private foundation developing a model for holistic change that is being replicated in underserved communities throughout the U.S, among others. Collectively, the case studies bring into the conversation the meaning that individuals bring to their spaces as members of diverse communities, as public and private actors seeking to effect change in underserved communities, and the tension that may result as place is redefined through philanthropic work. The themes and lessons learned that emerge from the case studies offer insights for practitioners, scholars and students of philanthropy.