An essential, sensitive overview on the current and future use of AI tools in the behavioral health care context. Advances in AI are making possible more personalized, precise, efficient, predictive, and portable behavioral health care. This overview offers an important resource for practitioners who want to understand how AI can be used to improve their practice and help clients monitor their health. AI is revolutionizing the delivery of behavioral health care for mental health care professionals and their clients. This handbook offers an accessible guide to this transformation. It explains the ways that AI tools are currently used in varied behavioral-health contexts, including office administration, research, assessment and diagnosis, and direct clinical care, and it identifies critical applications for future usage. The guide also presents the current and potential value of AI technology in professional training programs and patient self-care, suggesting important pathways to further development. Research grounds each chapter, bolstering the identification of the many opportunities for implementing AI to augment behavioral health, improve behavioral health outcomes, lower the costs of behavioral health care delivery, and benefit population health. Relevant ethical issues and safety concerns are sensitively discussed throughout.