The two-volume set LNCS 15701 + 15702 constitutes the proceedings of the 37th International Conference on Advanced Information Systems Engineering, CAiSE 2025, which was held in Vienna, Austria, during June 16&17, 2025. The 35 papers included in the proceedings were carefully reviewed and selected from 229 submissions. They were organized in topical sections as follows: Part I: Modelling with LLM; Security; Sustainability; Chatbots and social networks; process monitoring; IS-development and usage; pre-processing and forecasting;  Part II: Comprehension, explanation and recommendation; process discovery; system architecture and privacy; conformance-checking; cloud systems; extending process modelling; ontologies and knowledge graphs.