Comprehensive guide offering actionable strategies for enhancing human-centered AI, efficiency, and productivity in industrial and systems engineering through the power of AI. Advances in Artificial Intelligence Applications in Industrial and Systems Engineering is the first book in the Advances in Industrial and Systems Engineering series, offering insights into AI techniques, challenges, and applications across various industrial and systems engineering (ISE) domains. Not only does the book chart current AI trends and tools for effective integration, but it also raises pivotal ethical concerns and explores the latest methodologies, tools, and real-world examples relevant to today’s dynamic ISE landscape. Readers will gain a practical toolkit for effective integration and utilization of AI in system design and operation. The book also presents the current state of AI across big data analytics, machine learning, artificial intelligence tools, cloud-based AI applications, neural-based technologies, modeling and simulation in the metaverse, intelligent systems engineering, and more, and discusses future trends. Written by renowned international contributors for an international audience, Advances in Artificial Intelligence Applications in Industrial and Systems Engineering includes information on: Reinforcement learning, computer vision and perception, and safety considerations for autonomous systems (AS) (NLP) topics including language understanding and generation, sentiment analysis and text classification, and machine translation AI in healthcare, covering medical imaging and diagnostics, drug discovery and personalized medicine, and patient monitoring and predictive analysis Cybersecurity, covering threat detection and intrusion prevention, fraud detection and risk management, and network security Social good applications including poverty alleviation and education, environmental sustainability, and disaster response and humanitarian aid. Advances in Artificial Intelligence Applications in Industrial and Systems Engineering is a timely, essential reference for engineering, computer science, and business professionals worldwide.