This book constitutes the refereed proceedings of three workshops symposia, held at the 41st International Conference on Conceptual Modeling, ER 2022, as a virtual event, in October 2022. The 11 papers deal with topics such as foundations; business information systems; advanced and cross-disciplinary applications, conceptual modeling, information systems and knowledge graphs; data/object management; engineering; and experience. The following workshops are included in this volume: Third International Workshop on Conceptual Modeling for Life Sciences (CMLS), 5th International Workshop on Empirical Methods in Conceptual Modeling (EmpER); and First International Workshop on Digital Justice, Digital Law and Conceptual Modeling (JUSMOD).