With the recent pandemic emergency, many people are spending their days in smart working and have increased their use of digital resources for both work and entertainment. The result is that the amount of digital information handled online is dramatically increased, and we can observe a significant increase in the number of attacks, breaches, and hacks. This Special Issue aims to establish the state of the art in protecting information by mitigating information risks. This objective is reached by presenting both surveys on specific topics and original approaches and solutions to specific problems. In total, 16 papers have been published in this Special Issue.