This book presents state-of-the-art blockchain and AI advances in health care. Healthcare service is increasingly creating the scope for blockchain and AI applications to enter the biomedical and healthcare world. Today, blockchain, AI, ML, and deep learning are affecting every domain. Through its cutting-edge applications, AI and ML are helping transform the healthcare industry for the better. Blockchain is a decentralization communication platform that has the potential to decentralize the way we store data and manage information. Blockchain technology has potential to reduce the role of middleman, one of the most important regulatory actors in our society. Transactions are simultaneously secure and trustworthy due to the use of cryptographic principles. In recent years, blockchain technology has become very trendy and has penetrated different domains, mostly due to the popularity of cryptocurrencies. One field where blockchain technology has tremendous potential is health care, dueto the need for a more patient-centric approach in healthcare systems to connect disparate systems and to increase the accuracy of electronic healthcare records (EHRs).