The improvements in local anesthetic agents and techniques for local anesthetic administration are probably the most important advances in the field of dentistry. Articaine is a safe alternative to Lignocaine, which is potent and effective. The advantage of Articaine over other anesthetics is its potency due to high lipo-solubility attributed to thiopene ring in its molecule.The long duration of action and its superior diffusion through bony tissue makes it comparable to long acting local anesthetics.