Eccentric millionaire David Van Wyck has decided to pledge all his money away, leaving his wife Anne nothing but her jewelry to survive on. When David sees Anne flirting with an old high school friend during a weekend party at his mansion, Buttonwood Terrace, he decides to include Anne's gems in his giveaway. David Wyck is found murdered the next morning in a locked-room and while suspicion initially points to Anne, it becomes apparent that several of Wyck's guests had a motive for the crime. The narrator of the story, the guest Ann is in love with, prays that the culprit is 'Anybody but Anne.'