This book constitutes thoroughly refereed and revised selected papers from the 10th Iberoamerican Conference on Applications and Usability of Interactive TV, jAUTI 2021, held in Sangolqui, Ecuador, during December 2-3, 2021. The 9 full papers included in this book were carefully reviewed and selected from 25 submissions. They were organized in topical sections as follows: Usability and UX; interaction techniques and accesibility; and technologies, services, and applications for interactive digital TV.