This Springer book provides a perfect platform to submit chapters that discuss the prospective developments and innovative ideas in artificial intelligence and machine learning techniques in the diagnosis of COVID-19. COVID-19 is a huge challenge to humanity and the medical sciences. So far as of today, we have been unable to find a medical solution (Vaccine). However, globally, we are still managing the use of technology for our work, communications, analytics, and predictions with the use of advancement in data science, communication technologies (5G & Internet), and AI. Therefore, we might be able to continue and live safely with the use of research in advancements in data science, AI, machine learning, mobile apps, etc., until we can find a medical solution such as a vaccine. We have selected eleven chapters after the vigorous review process. Each chapter has demonstrated the research contributions and research novelty. Each group of authors must fulfill strict requirements.