This book provides an in-depth look into the transformative world of AI Surgery, offering a detailed examination of its recent advances and future potential. Beginning with a clear definition and classification of "AI Surgery," the book sets the stage for understanding how artificial intelligence is reshaping surgical practices. It addresses the pressing need for data standardization and cybersecurity, crucial for the effective implementation of AI in medical environments. The chapters cover a wide range of topics, including the development of Smart Cyber Operating Theaters and the intricacies of surgical process and semantic data modeling. The book also tackles regulatory and ethical issues, providing a comprehensive overview of the challenges faced by AI Surgery. Real-world clinical cases in neurosurgery, orthopedic surgery, eye surgery, and laparoscopic surgery illustrate the practical applications of AI, while future trends such as AI-driven robotics, telesurgery using 5G, and AI-enhanced theranostics are explored in detail. Readers will find contributions from leading experts in the field, offering diverse perspectives and insights. The book invites readers to consider critical questions about the future of surgery and the role of AI in enhancing surgical outcomes. It is a vital resource for medical engineers, AI researchers, and medical doctors interested in cutting-edge medical technologies. It serves as a foundation for future advancements in AI Surgery, making it an essential read for professionals seeking to understand and contribute to the future of surgical innovation.