The CDC Yellow Book has been a trusted resource among healthcare professionals for over half a century. It compiles the US government's current travel health guidance, providing travel medicine specialists, healthcare professionals, and travelers with expert guidance for safe and healthy international travel. Along with disease-specific prevention and treatment recommendations, this comprehensive reference text equips readers with the background and context needed to understand and address public health threats associated with all types of international travel. With chapters written by subject matter experts in the travel medicine field, this edition features the following topics: Vetted recommendations for pre-travel vaccinations and preventative care, including public health guidance for specific destinations and types of travel Profiles of the most common travel-associated infections and health conditions Special sections tailored to travelers with additional considerations, including travelers with HIV, immunocompromised travelers, severely allergic travelers, and travelers with substance use disorders Updated advice for family travel, including pregnant travelers, traveling safely with infants and children, and traveling with pets and service animals Illustrated with vividly drawn destination maps conveying the endemicity of malaria, yellow fever, and other infectious diseases Expanded section on pre- and post-arrival medical evaluations for refugees, immigrants, and other migrant populations Expanded content on the clinical approach to international travelers returning with respiratory complaints, diarrhea, dermatologic conditions, parasitic disease, and more Public health guidance for popular itineraries in Africa and the Middle East, the Americas and the Caribbean, and Asia