While confronting many challenges related to changes in health care, higher education, and clinical practice, nurse educators are exploring new opportunities for innovative teaching/learning methods, new clinical models, and educational practices to provide high-quality education to promote optimal, quality patient care. Clinical simulations can provide health care educators one approach to create student-centered, experiential environments that engage and prepare the learner for real-world practice. Clinical Simulations in Nursing Education: Advanced Concepts, Trends, and Opportunities provides chapters authored by expert simulation researchers, educators, and users to shed light on important advancements and emerging topics in clinical simulation including:  • Enhanced interprofessional education and practice through simulation  • Meaningful debriefing  • Expansion of clinical simulation globally  • Development of a good business plan and consideration of the economic model of a simulation center  • Research and evaluation of clinical simulation  • High-stakes simulation  • Certification of educators and accreditation of simulation centers