This book aims at meeting the challenge of getting along with today's unprecedented rate of innovation supported by disruptive digital technologies, which changed the perception of the productivity and effectiveness and opened a gateway to more than ever dynamic advances in solving the important societal challenges."Disruptive Information Technologies for a Smart Society" is the proceedings book of the 14th International Conference for Information Society and Technologies that brings together experts from various fields to discuss the latest advancements in industrial AI, digitalization in health, well-being and sport, enterprise information systems, large language models, and security and safety.The book and the conference serve as a platform for researchers of all career stages in technical sciences, especially Ph.D. students, practitioners, and industry experts in health care, AI and other areas to share and learn on the cutting-edge technologies and stay at the forefront of these rapidly evolving fields.