The face is the first book of humanity. This is an invitation to reread it in the light of contemporary neuroscience. The face is the first universal alphabet of the human species. A biological alphabet, inscribed in the facial muscles, regulated by specific neuronal circuits and guided by survival imperatives. Each contraction, each subtle activation, each neuromicroexpression represents a minimum unit of meaning, a neurobiological letter that the brain writes and the world learns to read, defends Prof. Freitas-Magalhães, the world's leading expert for Neuroscience and Biobehavioral Psychology and the Encyclopedia of Human Behavior, by Elsevier, Oxford, in his pioneering and extraordinary book on the face as a universal alphabet.