This comprehensive handbook provides an overview of current trends in computer-assisted language learning (CALL) teacher education and professional development across the globe. It highlights theories and practices in CALL teacher education and professional development in five sections, such as English language teaching, including pre-service teachers, in-service teachers, teacher educators, material developers, course designers and researchers. It explores the role of CALL teacher education and professional development in many underexplored countries such as Africa, Asia, Eastern Europe and the Middle East. It stresses the critical role of professional development programs, from the use of technology in its generic sense. The theoretical and empirical chapters in the book provide a more inclusive and comprehensive picture of various aspects of CALL teacher education and professional development globally. It offers context-specific approaches and strategies to language teachers andteacher educators. It provides pedagogical implications and suggestions for promoting digital literacy and autonomy in online education. This book provides valuable insights for researchers, teacher educators and teacher trainers in applied linguistics.