Higher education institutions have already begun to see decreasing enrollment numbers, even as higher education enrollment is predicted to drop precipitously starting in 2025. Much of the decrease in enrollment will be driven by demographic trends about which higher education institutions can do little, making the retention of students who do enroll that much more important. Overall retention rates have stagnated and differential retention rates by race and ethnicity have persisted. If higher education institutions, researchers, and policy makers are to improve retention rates, a critical examination of the current state and future directions of retention research is essential.This edited volume begins that examination by addressing several questions: What are the needed directions in theory and research on college student persistence and how do we translate new theory and research into effective practices? Are we asking the right questions, looking in the right places, or trying to apply out-of-date theories to new populations? In short, how can the research community help institutions improve retention in this challenging time?