This book constitutes the refereed proceedings of the 6th EAI International Conference on Industrial Networks and Intelligent Systems, INISCOM 2020, held in Hanoi, Vietnam, in August 2020. Due to COVID-19 pandemic the conference was held virtually.The 26 full papers were selected from 59 submissions and are organized thematically in tracks on telecommunications systems and networks; hardware, software and application designs; information processing and data analysis; industrial networks and intelligent systems; security and privacy.