Ion -Selective Electrodes for Biological Systems provides a user-friendly and practical guide to the manufacture and use of ion-selective electrodes for a wide variety of experimental systems used in biology. The book is aimed at researchers with little practical experience in the field and will direct them through the steps involved in making electrodes, interpretation of the data, requirements of the recording apparatus, potential pitfalls involved in their use, and the range of situations in which they can be used. This is the first book that deals comprehensively with such practical details and will enable the reader to become competent in the use of ion-selective electrodes.