The use of minimally invasive spine surgery (MISS) has grown rapidly over the last decade and remains the fastest growing area in spine surgery. Now in a revised and expanded second edition including 19 new chapters, this comprehensive textbook provides an updated presentation of the field of MISS, highlighting surgical techniques and clinical outcomes as well as providing a unique focus on how these techniques are applied for specific spinal conditions. Minimally Invasive Spine Surgery, Second Edition  includes detailed discussions of enabling technologies, surgical techniques, approaches to specific diseases and conditions, a new section on out-patient/ambulatory spine surgery, and strategies to manage the unique risks and complications associated with MISS. Each chapter, whether revised or new, is formatted in a consistent manner, including bulleted key learning points as well as review questions, pearls and pitfalls, and generous illustrations and intra-operative photographs. Written and edited by thought leaders in the field, this user-friendly textbook will be an essential resource for orthopedic and neurosurgery trainees, as well as a valuable reference and review for spine surgeons and health care professionals who treat the spine.