This volume records and disseminates selected papers from the Stinson66 conference, including surveys, prospectives, and papers presenting original and current research. It contains four accessible surveys of topics in combinatorial designs and related topics, ranging from a tutorial survey of connections to classical group theory, to surveys of "hot topics" in current research. It also contains a prospective paper identifying topics for future research efforts, co-authored by one of the elder statesmen of the field, Alex Rosa. Finally, the research papers examine topics ranging from pure mathematics to applied work in computing, networking, communications, and cryptography. For students and newcomers to these topics, the volume provides accessible survey material that does not have onerous prerequisites. The breadth of topics reflects the vibrancy of the field in a way that can be appreciated by all researchers. The papers present important advances on theory and applications,which also benefit advanced researchers.