This book strengthens the scientific knowledge base and promotes rational thinking among students The Medical Council of India (MCI) has introduced a competency-based curriculum in 2019, which not only lays emphasis on integration with clinical and pre-clinical subjects but also clearly states subject competencies and defines domains and levels to be achieved for each of them. In addition, it is clinically oriented and gives due importance to the self-directed learning. The duration of teaching for the subject of Pharmacology in the new curriculum has been reduced to one year with additional dedicated time to revisit it in the subsequent years. This 26th edition of Pharmacology and Pharmacotherapeutics has been revised considerably to match the demands of the new curriculum. Right from its conception, this book has used an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. We have made every attempt to provide up-to-date information about the drugs while focussing on the aspects relevant to their use in clinical practice. - Structured pedagogy facilitating feature-rich presentation and organization of the content, which makes it more student friendly　 - Richly illustrated content supplemented with large number of tables and boxes – explaining physiology, complex concepts, relevant drug features and principles of pharmacotherapy - Mechanisms of drug actions, explained in text and illustrated via diagrams as well as videos (animations) for better understanding and retention - Key points in pharmacology and pharmacotherapy of diseases highlighted throughout the book - Practical tips in this book serve as a reference guide in practice so that students can treat their patients effectively and confidently