This book presents the dynamic modeling and attitude control of flexible spacecraft with time-varying parameters. The dynamic characteristics, vibration control methods and attitude stabilization methods for spacecraft are systematically studied in respects of the theoretical modeling, numerical simulation and the ground experiment. Three active control theories in complex mode space are presented for flexible space structures. Optimal slew strategies based on variable amplitudes input shaping methods and coupling control methods are proposed for stabilization of flexible spacecraft. The research provides an important way to solve the problem of high-precision attitude control of flexible spacecraft with time-varying parameters. This book is appropriate for the researchers who focus on the multi-body dynamics, attitude and vibration control of flexible spacecraft.