ISIS has unleashed a weaponized version of the deadly Ebola virus, killing 97 percent of the world's population. Only the immune and those who hunkered down in remote locations remain. Through the chaos that remains strides a giant of a man known only as Stryker. He is a former Force Recon Marine, who has lost as much as anyone, but fights to preserve his honor and creed in the face of slave traders and rogue military elements who prey on the innocent. Together with his former drill instructor, Sarge, they struggle to eliminate the remaining evil elements in society, even as the nation's infrastructure crumbles and life becomes considerably more difficult.