Chloe Chantel is an artist who lives in the French Quarter of New Orleans and is descended from a long line of Voodoo Queens. She is approached by a stranger who makes an odd request. The man offers to pay Chloe $50,000 to paint a self-portrait. After Chloe agrees, her most famous ancestor comes to her in a dream and reveals the stranger's ulterior motive. When Chloe completes the portrait, she is again hounded by the handsome Adrien Simpkin, a homicide detective with the NOPD. Chloe realizes she will have to use all the powers that she inherited from her ancestors if she hopes to survive the strangers evil plot, and to escape Detective Simpkin's efforts to have her prosecuted for the murders of three missing wealthy men.