Understanding Major Depressive Disorder , Third Edition anatomical chart features sections that define depression and describe how it affects the brain, contributing factors, signs and symptoms, and treatment, including an illustrated box on the role of neurotransmitters. Featured sections: How Does Depression Affect the Brain Changes in Parts of the Limbic System can Affect Mood and Behavior What is Depression? Several Factors can Contribute to Depression Signs and Symptoms of Major Depressive Disorder Treatment Boxed feature on Chemical Imbalance with coverage of The Role of Neurotransmitters. Illustrations included: Neurons: Abnormal and Normal Brain: Amygdala, Hypothalamus, and Thalamus 20" x 26" heavyweight paper laminated with grommets at top corners