RNA Interference: Challenges and Therapeutic Opportunitiesprovides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA's unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successfulMethods in Molecular Biologyseries, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunitieswill aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies. | RNA Interference by Mouldy Sioud, Hardcover | Indigo Chapters